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this.panel_Playlists.AutoScroll = false;
this.panel_Playlists.HorizontalScroll.Enabled = false;
this.panel_Playlists.HorizontalScroll.Visible = false;
this.panel_Playlists.VerticalScroll.Enabled = false;
this.panel_Playlists.VerticalScroll.Visible = false;
this.panel_Playlists.AutoScroll = true;                    

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public enum ScrollBarDirection
{
    SB_HORZ = 0,
    SB_VERT = 1,
    SB_CTL = 2,
    SB_BOTH = 3
}

[DllImport("user32.dll")]
[return: MarshalAs(UnmanagedType.Bool)]
private static extern bool ShowScrollBar(IntPtr hWnd, int wBar, bool bShow);

protected override void WndProc(ref Message m)
{
    ShowScrollBar(panel_Playlists.Handle, (int)ScrollBarDirection.SB_BOTH, false);
    base.WndProc(ref m);
}                    

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Panel outerPanel = new Panel();
outerPanel.AutoSize = false;
outerPanel.AutoScroll = false;
// For testing make the bounds very obvious
outerPanel.BackColor = Color.Red;
outerPanel.BorderStyle = BorderStyle.FixedSingle;

Panel innerPanel = new Panel();
innerPanel.Parent = outerPanel;
innerPanel.AutoSize = true;
innerPanel.AutoSizeMode = AutoSizeMode.GrowAndShrink;
innerPanel.AutoScroll = false;
innerPanel.BorderStyle = BorderStyle.FixedSingle;
innerPanel.BackColor = Color.Blue;

// Scroll down a bit, right a bit
innerPanel.Location = new Point(-50, -30);